|
GO:0032991
|
protein-containing complex
|
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
|
GO:0005737
|
cytoplasm
|
The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
|
GO:0005575
|
cellular_component
|
A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). |
|
GO:0005622
|
intracellular anatomical structure
|
A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. |
|
GO:0110165
|
cellular anatomical structure
|
A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. |
|
GO:0043227
|
membrane-bounded organelle
|
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
|
GO:0043226
|
organelle
|
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. |
|
GO:0043229
|
intracellular organelle
|
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
|
GO:0043231
|
intracellular membrane-bounded organelle
|
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
|
GO:0098796
|
membrane protein complex
|
Any protein complex that is part of a membrane. |
|
GO:0012505
|
endomembrane system
|
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. |
|
GO:0031984
|
organelle subcompartment
|
A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle. |
|
GO:0016020
|
membrane
|
A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. |
|
GO:0031090
|
organelle membrane
|
A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. |
|
GO:0005789
|
endoplasmic reticulum membrane
|
The lipid bilayer surrounding the endoplasmic reticulum. |
|
GO:0140534
|
endoplasmic reticulum protein-containing complex
|
A protein complex that is part of an endoplasmic reticulum. |
|
GO:0098827
|
endoplasmic reticulum subcompartment
|
A distinct region of the endoplasmic reticulum. |
|
GO:0005783
|
endoplasmic reticulum
|
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
|
GO:0042175
|
nuclear outer membrane-endoplasmic reticulum membrane network
|
The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane. |
|
GO:0034098
|
VCP-NPL4-UFD1 AAA ATPase complex
|
A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry). |
|
GO:0036501
|
UFD1-NPL4 complex
|
A dimeric protein complex that contains the co-factors for the ATPase VCP/p97 (Cdc48p in budding yeast). In mammals, this complex consists of UFD1L (UFD1) and NPLOC4 (NPL4). In budding yeast, the complex is a dimer of Ufd1p and Npl4p. |
