WormMine: Phenotype WBPhenotype:0000585 cell homeostasis metabolism variant

• Description: Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the cell compared to control.

2 RNAi

WormBase ID
WBRNAi00095298
WBRNAi00059923

2 RNAi Not Observed

WormBase ID
WBRNAi00063892
WBRNAi00063893

12 Children

Identifier	Name	Description
WBPhenotype:0001644	protein metabolism variant	Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of proteins in the organism compared to control.
WBPhenotype:0000736	autophagy variant	Animals exhibit variations in the process by which their cells digest parts of their own cytoplasm, compared to control.
WBPhenotype:0000773	chromosome segregation variant	Any variation in the processes that regulate the apportionment of chromosomes to each of two daughter cells compared to control.
WBPhenotype:0000000	chromosome instability	Variations in the frequencies of translocations, inversions, deletions, or gene amplifications and variations in chromosome fusion events and or chromosomal loss compared to control.
WBPhenotype:0000142	cell stress response variant	Variations in the activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress, compared to control. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
WBPhenotype:0001827	RNA metabolism variant	Variations in any process that involves the maintenance, biosynthesis or accumulation of RNA in the organism compared to control.
WBPhenotype:0000732	DNA metabolism variant	Variations in any process that involves the maintenance, biosynthesis or accumulation of DNA in the organism compared to control.
WBPhenotype:0002236	endo lysosomal degradation pathway defective	The degradation of endocytosed and intracellular material does not occur to the same extent as it does in control animals.
WBPhenotype:0001673	telomere homeostasis variant	Animals exhibit variations in the processes that affect and monitor the activity of telomeric proteins and the length of telomeric DNA, which allow the chromosome to persist from generation to generation, compared to control.
WBPhenotype:0001393	cell acidification variant	Variations in the processes that reduce the internal pH of a cell (measured by the concentration of the hydrogen ion), compared to control.
WBPhenotype:0001283	organelle metabolism variant	Variations in the chemical reactions and pathways of an organelle compared to control.
WBPhenotype:0000767	integrity of membranous organelles defective early emb	Sparse or enlarged yolk granules.

1 Data Sets

• WormBaseAcedbConverter

1 Parents

Identifier	Name	Description
WBPhenotype:0000536	cell physiology phenotype	Animals exhibit variations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for the cell to carry out its normal functions or be able to perceive and respond to stimuli, compared to control animals.

4 Phenotype Allele

Public Name
gk133
eh5
ok1035
tm1937

0 Phenotype Allele Not Observed

1 Synonyms

• Name: cell homeostasis metabolism abnormal