WormMine: Phenotype WBPhenotype:0001496 metaphase to anaphase transition defect

• Description: Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids (or homologous chromosomes) separate and migrate towards the poles of the spindle.

0 RNAi

0 RNAi Not Observed

2 Children

Identifier	Name	Description
WBPhenotype:0001216	meiosis metaphase to anaphase transition block	Oocyte chromosomes arrest in metaphase of meiosis I without transitioning to anaphase or producing polar bodies.
WBPhenotype:0001497	mitotic metaphase to anaphase transition defect	Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids separate and migrate towards the poles of the spindle.

1 Data Sets

• WormBaseAcedbConverter

1 Parents

Identifier	Name	Description
WBPhenotype:0000740	cell cycle variant	Cells of the animals exhibit variations in the initiation, progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals.

5 Phenotype Allele

Public Name
h1983
g48
ku233
h1960
t1668

0 Phenotype Allele Not Observed

2 Synonyms

• Name: metaphase to anaphase transition fails

• Name: Mat