WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0036487 nitric-oxide synthase inhibitor activity GO

Namespace  molecular_function Obsolete  false
Description  Binds to and stops, prevents or reduces the activity of nitric oxide synthase.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

17 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0005515 protein binding Binding to a protein.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.
GO:0004497 monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
GO:0019899 enzyme binding Binding to an enzyme, a protein with catalytic activity.
GO:0030234 enzyme regulator activity Binds to and modulates the activity of an enzyme.
GO:0004857 enzyme inhibitor activity Binds to and stops, prevents or reduces the activity of an enzyme.
GO:0140678 molecular function inhibitor activity A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
GO:0004517 nitric-oxide synthase activity Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
GO:0050998 nitric-oxide synthase binding Binding to nitric-oxide synthase.
GO:0030235 nitric-oxide synthase regulator activity Binds to and modulates the activity of nitric oxide synthase.
GO:0036487 nitric-oxide synthase inhibitor activity Binds to and stops, prevents or reduces the activity of nitric oxide synthase.

25 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0004857 GO:0036487
is_a GO:0030235 GO:0036487
negatively regulates GO:0004517 GO:0036487
negatively regulates GO:0016709 GO:0036487
regulates GO:0004497 GO:0036487
has part GO:0005488 GO:0036487
negatively regulates GO:0016705 GO:0036487
has part GO:0003674 GO:0036487
regulates GO:0016709 GO:0036487
is_a GO:0140678 GO:0036487
is_a GO:0098772 GO:0036487
regulates GO:0003824 GO:0036487
regulates GO:0004517 GO:0036487
has part GO:0005515 GO:0036487
is_a GO:0003674 GO:0036487
regulates GO:0016491 GO:0036487
negatively regulates GO:0003674 GO:0036487
negatively regulates GO:0004497 GO:0036487
regulates GO:0003674 GO:0036487
negatively regulates GO:0003824 GO:0036487
has part GO:0050998 GO:0036487
negatively regulates GO:0016491 GO:0036487
has part GO:0019899 GO:0036487
regulates GO:0016705 GO:0036487
is_a GO:0030234 GO:0036487

2 Synonyms

Name Type
nitric oxide synthase inhibitor activity synonym
NOS inhibitor activity synonym