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WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0042557 eukaryotic elongation factor-2 kinase activator activity GO

Namespace  molecular_function Obsolete  false
Description  Binds to and increases the activity of the enzyme eukaryotic elongation factor-2 kinase.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

27 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0016301 kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0004674 protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
GO:0004672 protein kinase activity Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
GO:0016773 phosphotransferase activity, alcohol group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).
GO:0016772 transferase activity, transferring phosphorus-containing groups Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0005515 protein binding Binding to a protein.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0140677 molecular function activator activity A molecular function regulator that activates or increases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0019899 enzyme binding Binding to an enzyme, a protein with catalytic activity.
GO:0030234 enzyme regulator activity Binds to and modulates the activity of an enzyme.
GO:0004683 calcium/calmodulin-dependent protein kinase activity Calmodulin-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. This activity require the presence of calcium-bound calmodulin.
GO:0004686 elongation factor-2 kinase activity Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate.
GO:0019887 protein kinase regulator activity Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein.
GO:0019207 kinase regulator activity Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0019901 protein kinase binding Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
GO:0019900 kinase binding Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group.
GO:0008047 enzyme activator activity Binds to and increases the activity of an enzyme.
GO:0019209 kinase activator activity Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0030295 protein kinase activator activity Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.
GO:0042556 eukaryotic elongation factor-2 kinase regulator activity Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase.
GO:0042557 eukaryotic elongation factor-2 kinase activator activity Binds to and increases the activity of the enzyme eukaryotic elongation factor-2 kinase.
GO:0043539 protein serine/threonine kinase activator activity Binds to and increases the activity of a protein serine/threonine kinase.

39 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
positively regulates GO:0004686 GO:0042557
is_a GO:0043539 GO:0042557
is_a GO:0042556 GO:0042557
is_a GO:0140677 GO:0042557
has part GO:0005488 GO:0042557
regulates GO:0004674 GO:0042557
positively regulates GO:0016773 GO:0042557
positively regulates GO:0016772 GO:0042557
regulates GO:0003824 GO:0042557
is_a GO:0098772 GO:0042557
regulates GO:0016740 GO:0042557
regulates GO:0140096 GO:0042557
has part GO:0019899 GO:0042557
positively regulates GO:0004672 GO:0042557
regulates GO:0016301 GO:0042557
positively regulates GO:0004674 GO:0042557
positively regulates GO:0140096 GO:0042557
positively regulates GO:0003824 GO:0042557
regulates GO:0004672 GO:0042557
has part GO:0005515 GO:0042557
is_a GO:0030234 GO:0042557
has part GO:0003674 GO:0042557
regulates GO:0004686 GO:0042557
regulates GO:0003674 GO:0042557
positively regulates GO:0016301 GO:0042557
is_a GO:0008047 GO:0042557
positively regulates GO:0016740 GO:0042557
is_a GO:0003674 GO:0042557
is_a GO:0030295 GO:0042557
regulates GO:0016773 GO:0042557

1 Synonyms

Name Type
eEF-2 kinase activator synonym