WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0045541 negative regulation of cholesterol biosynthetic process GO

Namespace  biological_process Obsolete  false
Description  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

47 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0009058 biosynthetic process A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0008610 lipid biosynthetic process The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
GO:0006629 lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
GO:0044281 small molecule metabolic process The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
GO:0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
GO:0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
GO:0062012 regulation of small molecule metabolic process Any process that modulates the rate, frequency or extent of a small molecule metabolic process.
GO:0046165 alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
GO:0006066 alcohol metabolic process The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
GO:0008202 steroid metabolic process The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
GO:1902652 secondary alcohol metabolic process The chemical reactions and pathways involving secondary alcohol.
GO:0006694 steroid biosynthetic process The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
GO:1902653 secondary alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of secondary alcohol.
GO:0006695 cholesterol biosynthetic process The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
GO:0008203 cholesterol metabolic process The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
GO:0016126 sterol biosynthetic process The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
GO:0016125 sterol metabolic process The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

68 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
negatively regulates GO:0006695 GO:0045541
is_a GO:1902931 GO:0045541
is_a GO:0090206 GO:0045541
is_a GO:0106119 GO:0045541
is_a GO:0045540 GO:0045541
negatively regulates GO:0006695 GO:0045541
is_a GO:0065007 GO:0045541
negatively regulates GO:0046165 GO:0045541
negatively regulates GO:0006629 GO:0045541
is_a GO:0046890 GO:0045541
is_a GO:0050794 GO:0045541
is_a GO:0080090 GO:0045541
negatively regulates GO:1902652 GO:0045541
regulates GO:0006695 GO:0045541
negatively regulates GO:0009058 GO:0045541
regulates GO:0006694 GO:0045541
negatively regulates GO:1902653 GO:0045541
negatively regulates GO:0006066 GO:0045541
is_a GO:0048519 GO:0045541
negatively regulates GO:0008202 GO:0045541
negatively regulates GO:0008203 GO:0045541
is_a GO:0050789 GO:0045541
regulates GO:0006629 GO:0045541
is_a GO:0106118 GO:0045541
negatively regulates GO:0016125 GO:0045541
regulates GO:0046165 GO:0045541
negatively regulates GO:0016126 GO:0045541
regulates GO:0008203 GO:0045541
negatively regulates GO:0006694 GO:0045541
is_a GO:0009892 GO:0045541

8 Synonyms

Name Type
down regulation of cholesterol biosynthetic process synonym
down-regulation of cholesterol biosynthetic process synonym
downregulation of cholesterol biosynthetic process synonym
inhibition of cholesterol biosynthetic process synonym
negative regulation of cholesterol anabolism synonym
negative regulation of cholesterol biosynthesis synonym
negative regulation of cholesterol formation synonym
negative regulation of cholesterol synthesis synonym