WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0050709 negative regulation of protein secretion GO
Namespace  biological_process Obsolete  false
Description  Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
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0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

2 Ontology Annotations

Annotation Extension Qualifier
has_input(WB:WBGene00001445)|happens_during(WBls:0000039) involved_in
  involved_in

39 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0051234 establishment of localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0051641 cellular localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.
GO:0071705 nitrogen compound transport The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0033036 macromolecule localization Any process in which a macromolecule is transported to, or maintained in, a specific location.
GO:0046903 secretion The controlled release of a substance by a cell or a tissue.
GO:0140352 export from cell The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis.
GO:0032940 secretion by cell The controlled release of a substance by a cell.
GO:0032879 regulation of localization Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
GO:1903531 negative regulation of secretion by cell Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.
GO:1903530 regulation of secretion by cell Any process that modulates the frequency, rate or extent of secretion by cell.
GO:0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051048 negative regulation of secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
GO:0051046 regulation of secretion Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
GO:0009306 protein secretion The controlled release of proteins from a cell.
GO:0035592 establishment of protein localization to extracellular region The directed movement of a protein to a specific location within the extracellular region.
GO:0008104 protein localization Any process in which a protein is transported to, or maintained in, a specific location.
GO:0070727 cellular macromolecule localization Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GO:0071692 protein localization to extracellular region Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.
GO:0015031 protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0045184 establishment of protein localization The directed movement of a protein to a specific location.

70 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0050709 GO:0046676
is_a GO:0051224 GO:0050709
is_a GO:0050708 GO:0050709
negatively regulates GO:0009306 GO:0050709
negatively regulates GO:0009306 GO:0050709
is_a GO:1903531 GO:0050709
is_a GO:0065007 GO:0050709
negatively regulates GO:0006810 GO:0050709
regulates GO:0051179 GO:0050709
negatively regulates GO:0045184 GO:0050709
is_a GO:0032879 GO:0050709
is_a GO:1903828 GO:0050709
negatively regulates GO:0033036 GO:0050709
is_a GO:0050789 GO:0050709
negatively regulates GO:0032940 GO:0050709
regulates GO:0071705 GO:0050709
negatively regulates GO:0046903 GO:0050709
regulates GO:0008150 GO:0050709
is_a GO:0060341 GO:0050709
regulates GO:0006810 GO:0050709
regulates GO:0045184 GO:0050709
regulates GO:0051641 GO:0050709
negatively regulates GO:0051234 GO:0050709
is_a GO:0051046 GO:0050709
regulates GO:0033036 GO:0050709
regulates GO:0032940 GO:0050709
is_a GO:0050794 GO:0050709
is_a GO:0051048 GO:0050709
is_a GO:0051049 GO:0050709
negatively regulates GO:0071705 GO:0050709

4 Synonyms

Name Type
down regulation of protein secretion synonym
downregulation of protein secretion synonym
down-regulation of protein secretion synonym
inhibition of protein secretion synonym