WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0046826 negative regulation of protein export from nucleus GO

Namespace  biological_process Obsolete  false
Description  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

58 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0051234 establishment of localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0005622 intracellular anatomical structure A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.
GO:0110165 cellular anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0051168 nuclear export The directed movement of substances out of the nucleus.
GO:0051649 establishment of localization in cell Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0051641 cellular localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.
GO:0006913 nucleocytoplasmic transport The directed movement of molecules between the nucleus and the cytoplasm.
GO:0046907 intracellular transport The directed movement of substances within a cell.
GO:0051169 nuclear transport The directed movement of substances into, out of, or within the nucleus.
GO:0071705 nitrogen compound transport The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0043227 membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0005634 nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0043231 intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0033036 macromolecule localization Any process in which a macromolecule is transported to, or maintained in, a specific location.
GO:0032879 regulation of localization Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
GO:0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0008104 protein localization Any process in which a protein is transported to, or maintained in, a specific location.

88 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0046823 GO:0046826
is_a GO:0090317 GO:0046826
is_a GO:0046825 GO:0046826
negatively regulates GO:0006611 GO:0046826
is_a GO:0051457 GO:0046826
is_a GO:0065007 GO:0046826
negatively regulates GO:0006611 GO:0046826
regulates GO:0051234 GO:0046826
negatively regulates GO:0009987 GO:0046826
is_a GO:0051179 GO:0046826
part of GO:0070727 GO:0046826
is_a GO:0051651 GO:0046826
negatively regulates GO:0051168 GO:0046826
negatively regulates GO:0051641 GO:0046826
negatively regulates GO:0051169 GO:0046826
is_a GO:0072595 GO:0046826
occurs in GO:0043226 GO:0046826
occurs in GO:0043227 GO:0046826
negatively regulates GO:0015031 GO:0046826
negatively regulates GO:0006913 GO:0046826
occurs in GO:0043229 GO:0046826
part of GO:0051641 GO:0046826
occurs in GO:0005622 GO:0046826
is_a GO:0051051 GO:0046826
is_a GO:0046822 GO:0046826
part of GO:0009987 GO:0046826
is_a GO:0070201 GO:0046826
is_a GO:0048523 GO:0046826
regulates GO:0051641 GO:0046826
regulates GO:0051168 GO:0046826

8 Synonyms

Name Type
down regulation of protein export from nucleus synonym
down-regulation of protein export from nucleus synonym
downregulation of protein export from nucleus synonym
inhibition of protein export from nucleus synonym
negative regulation of protein export from cell nucleus synonym
negative regulation of protein export out of nucleus synonym
negative regulation of protein transport from nucleus to cytoplasm synonym
negative regulation of protein-nucleus export synonym