7 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0003674 | molecular_function | A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
| GO:0003824 | catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
| GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors | Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. |
| GO:0016491 | oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. |
| GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP. |
| GO:0035671 | enone reductase activity | Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+. |
| GO:0047787 | Delta4-3-oxosteroid 5beta-reductase activity | Catalysis of the reaction: a 3-oxo-5beta-steroid + NADP+ = a 3-oxo-Delta(4)-steroid + H+ + NADPH. The enzyme from human efficiently catalyzes the reduction of progesterone, androstenedione, 17alpha-hydroxyprogesterone and testosterone to 5beta-reduced metabolites; it can also act on aldosterone, corticosterone and cortisol, but to a lesser extent. The bile acid intermediates 7alpha,12alpha-dihydroxy-4-cholesten-3- one and 7alpha-hydroxy-4-cholesten-3-one can also act as substrates. |
6 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| is_a | GO:0035671 | GO:0047787 |
| is_a | GO:0016627 | GO:0047787 |
| is_a | GO:0016628 | GO:0047787 |
| is_a | GO:0003824 | GO:0047787 |
| is_a | GO:0016491 | GO:0047787 |
| is_a | GO:0003674 | GO:0047787 |
30 Synonyms
| Name | Type |
|---|---|
| cholestenone 5b-reductase activity | synonym |
| cholestenone 5-beta-reductase activity | synonym |
| cortisone 5-beta-reductase activity | synonym |
| cholestenone 5beta-reductase activity | synonym |
| cortisone b-reductase activity | synonym |
| cortisone 5beta-reductase activity | synonym |
| cortisone delta(4)-5-beta-reductase activity | synonym |
| cortisone beta-reductase activity | synonym |
| Delta(4)-3-ketosteroid 5-beta-reductase activity | synonym |
| cortisone delta4-5beta-reductase activity | synonym |
| Delta(4)-hydrogenase activity | synonym |
| Delta(4)-5-beta-reductase activity | synonym |
| Delta4-3-oxosteroid 5-beta-reductase activity | synonym |
| Delta4-3-ketosteroid 5beta-reductase activity | synonym |
| Delta4-hydrogenase activity | synonym |
| Delta4-5beta-reductase activity | synonym |
| steroid 5beta-reductase activity | synonym |
| steroid 5-beta-reductase activity | synonym |
| testosterone 5beta-reductase activity | synonym |
| testosterone 5-beta-reductase activity | synonym |
| GO:0047752 | alt_id |
| 3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase activity | synonym |
| 3-oxo-Delta4-steroid 5beta-reductase activity | synonym |
| 3-oxo-Delta(4)-steroid 5-beta-reductase activity | synonym |
| 5-beta-reductase activity | synonym |
| 4,5beta-dihydrocortisone:NADP+ delta4-oxidoreductase activity | synonym |
| 5beta-reductase activity | synonym |
| 5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase activity | synonym |
| androstenedione 5beta-reductase activity | synonym |
| androstenedione 5-beta-reductase activity | synonym |
