1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00020114 | pde-4 | R153.1 | Caenorhabditis elegans |
| WormBase ID | WBStrain00023484 | CGC Received | 2006-06-08 |
| Genotype | pde-4(ce268) II. | Laboratory | CGC |
| Made By | WBPerson423 | Mutagen | EMS |
| Name | KG744 | Outcrossed | x5 |
| Remark | Hyperactive locomotion and hypersensitive to stimuli such as plate dropping. Restores wild type levels of locomotion to paralyzed ric-8(md303) mutants. Most, but not all adults, appear significantly Egl-c. Some mature adults are thinner than normal. Aldicarb sensitivity, growth rate, pumping, length, and distribution on food are all similar to wild type. The ce268 mutation is a D448N change relative to PDE-4D isoform. It disrupts the catalytic domain by changing one of the four active site residues that together chelate an active site zinc atom. Inheritance is semi-dominant due to dominant negative side effects. | Species | Caenorhabditis elegans |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00020114 | pde-4 | R153.1 | Caenorhabditis elegans |
