3 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00003183 | mei-1 | T01G9.5 | Caenorhabditis elegans |
| WBGene00006752 | unc-13 | ZK524.2 | Caenorhabditis elegans |
| WBGene00006843 | unc-119 | M142.1 | Caenorhabditis elegans |
| WormBase ID | WBStrain00026463 | CGC Received | 2014-03-27 |
| Genotype | mei-1(ct46) unc-13(e1091) I; unc-119(ed3) III; abcIs3. | Laboratory | CGC |
| Made By | WBPerson14050 | Mutagen | Microparticle bombardment |
| Name | MAS94 | Outcrossed | x0 |
| Remark | abcIs3 [pie-1p::ebp-2::GFP + unc-119(+)]. Embryonic-lethal at 25C due to dominant gain-of-function mutation mei-1(ct46), and Uncoordinated due to unc-13 mutation. Maternal expression of EBP-2::GFP microtubule end-binding protein. EBP-2 encodes an EB1-like protein (end-binding) that, in early embryos, locates to the growing tips of microtubules. A strong fluorescent signal localizes to the centrosomes of early embryos due to a high concentration of polymerizing microtubules. mei-1(ct46)-based ectopic microtubule severing causes mitotic spindle defects in the early embryo. References: Gusnowski EM, Srayko M. J Cell Biol. 2011 Aug 8;194(3):377-86. Tegha-Dunghu J, et al. Methods Mol Biol. 2014;1136:103-16. | Species | Caenorhabditis elegans |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00003183 | mei-1 | T01G9.5 | Caenorhabditis elegans |
| WBGene00006752 | unc-13 | ZK524.2 | Caenorhabditis elegans |
| WBGene00006843 | unc-119 | M142.1 | Caenorhabditis elegans |
