1 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00045237 | mrt-1 | F39H2.5 | Caenorhabditis elegans |
WormBase ID | WBStrain00040706 | CGC Received | 2013-04-29 |
Genotype | mrt-1(yp2) I. | Laboratory | CGC |
Made By | WBPerson7 | Name | YA1039 |
Outcrossed | x7 | Remark | yp2 mutation perturbs the MRT-1 DNA-binding domain. Mortal germline. Progressive telomere shortening due to telomerase dysfunction. Hypersensitive to DNA interstrand crosslinking agents. This strain will becomce sterile after propagating 10-20 generations. mrt-1 mutants can be rejuvenated by outcrossing. Reference: Meier B, et al. EMBO J. 2009 Nov 18;28(22):3549-63. |
Species | Caenorhabditis elegans |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00045237 | mrt-1 | F39H2.5 | Caenorhabditis elegans |