WormMine: Gene WBGene00226659

• WormBase Gene ID: WBGene00226659
• Gene Name: Bm6398
• Sequence Name: Bm6398
• Organism: Brugia malayi
• Automated Description: Is affected by 20-hydroxyecdysone based on proteomic studies. Is predicted to encode a protein with the following domains: FAD/NAD(P)-binding domain superfamily; FAD dependent oxidoreductase; GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1; FAD dependent oxidoreductase central domain; Aminomethyltransferase folate-binding domain; Glycine cleavage T-protein/YgfZ, C-terminal; Glycine cleavage T-protein C-terminal barrel domain; FAD dependent oxidoreductase, central domain; Glycine cleavage T-protein, C-terminal barrel domain; and Aminomethyltransferase, folate-binding domain. Is an ortholog of C. elegans Y37E3.17.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

2 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm6398b.1	Bm6398b.1		[unknown]
Transcript:Bm6398a.1	Bm6398a.1		[unknown]

Other

2 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm6398a	Bm6398a		[unknown]
CDS:Bm6398b	Bm6398b		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

• WormBaseAcedbConverter

0 Downstream Intergenic Region

2 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_F120_vs_F30
	Proteins that showed significantly increased expression in parasites exposed to 20-hydroxyecdysone.	An empirical filter of proteins with more than two peptides identified, a P value <0.05 and a greater than two-fold change of differential expression, was applied to the data. The Bonferroni correction was applied to correct the P value for the proteins analyzed.	WBPaper00049261:20-hydroxyecdysone_upregulated_protein

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term