WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Strain :

WormBase ID  WBStrain00034599 CGC Received  2000-04-21
Genotype  lin-5(ev571) II. Laboratory  CGC
Made By  WBPerson732 Mutagen  EMS
Name  SV124 Remark  Temperature sensitive - maintain at 15C. Recessive loss-of-function stronger with increases in temperature, nearly WT at 15C. At the non-permissive temperature DNA replication continues in the absence of mitosis. Mutants enter mitosis at the normal time and form bipolar spindles, but fail chromosome alignment at the metaphase plate, sister chromatid separation and cytokinesis. Molecular lesion is a 9 bp duplication followed by a T to C transversion. Mutagen was EMS but mutation likely caused by polymerase slippage.
Species  Caenorhabditis elegans

1 Alleles

Public Name
ev571

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002994 lin-5 T09A5.10 Caenorhabditis elegans