WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0051430 corticotropin-releasing hormone receptor 1 binding GO

Namespace  molecular_function Obsolete  false
Description  Binding to a corticotropin-releasing hormone receptor 1 (CRHR1). CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on corticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

10 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0005515 protein binding Binding to a protein.
GO:0005102 signaling receptor binding Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0001664 G protein-coupled receptor binding Binding to a G protein-coupled receptor.
GO:0051427 hormone receptor binding Binding to a receptor for a hormone.
GO:0071855 neuropeptide receptor binding Binding to a neuropeptide receptor.
GO:0051428 peptide hormone receptor binding Binding to a receptor for a peptide hormone.
GO:0051429 corticotropin-releasing hormone receptor binding Binding to a receptor for corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.
GO:0051430 corticotropin-releasing hormone receptor 1 binding Binding to a corticotropin-releasing hormone receptor 1 (CRHR1). CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on corticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system.

9 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0051429 GO:0051430
is_a GO:0005488 GO:0051430
is_a GO:0003674 GO:0051430
is_a GO:0005515 GO:0051430
is_a GO:0051428 GO:0051430
is_a GO:0001664 GO:0051430
is_a GO:0051427 GO:0051430
is_a GO:0071855 GO:0051430
is_a GO:0005102 GO:0051430

5 Synonyms

Name Type
CRHR1 binding synonym
type 1 corticotropin releasing factor receptor ligand synonym
type 1 corticotropin releasing factor receptor binding synonym
GO:0031743 alt_id
type 1 corticotropin-releasing factor receptor binding synonym