WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0051880 G-quadruplex DNA binding GO

Namespace  molecular_function Obsolete  false
Description  Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

1 Ontology Annotations

Annotation Extension Qualifier
  enables

5 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0003676 nucleic acid binding Binding to a nucleic acid.
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0051880 G-quadruplex DNA binding Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0003677 GO:0051880
is_a GO:0003674 GO:0051880
is_a GO:0003676 GO:0051880
is_a GO:0005488 GO:0051880
is_a GO:0051880 GO:0061849
regulates GO:0051880 GO:1905493
regulates GO:0051880 GO:1905493

8 Synonyms

Name Type
G quartet binding synonym
G-quartet binding synonym
G quadruplex DNA binding synonym
G quartet DNA binding synonym
G-DNA binding synonym
G-quartet DNA binding synonym
quadruplex DNA binding synonym
tetraplex DNA binding synonym