WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0051967 negative regulation of synaptic transmission, glutamatergic GO

Namespace  biological_process Obsolete  false
Description  Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

24 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0023052 signaling The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0007154 cell communication Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0010646 regulation of cell communication Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0023051 regulation of signaling Any process that modulates the frequency, rate or extent of a signaling process.
GO:0023057 negative regulation of signaling Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.
GO:0010648 negative regulation of cell communication Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0098916 anterograde trans-synaptic signaling Cell-cell signaling from pre to post-synapse, across the synaptic cleft.
GO:0099537 trans-synaptic signaling Cell-cell signaling in either direction across the synaptic cleft.
GO:0099536 synaptic signaling Cell-cell signaling to, from or within a synapse.
GO:0007268 chemical synaptic transmission The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
GO:0007267 cell-cell signaling Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
GO:0099177 regulation of trans-synaptic signaling Any process that modulates the frequency, rate or extent of trans-synaptic signaling.
GO:0050804 modulation of chemical synaptic transmission Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
GO:0050805 negative regulation of synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
GO:0035249 synaptic transmission, glutamatergic The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
GO:0051966 regulation of synaptic transmission, glutamatergic Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
GO:0051967 negative regulation of synaptic transmission, glutamatergic Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.

41 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
negatively regulates GO:0035249 GO:0051967
is_a GO:0051966 GO:0051967
is_a GO:0065007 GO:0051967
is_a GO:0050805 GO:0051967
negatively regulates GO:0035249 GO:0051967
negatively regulates GO:0099537 GO:0051967
negatively regulates GO:0050789 GO:0051967
negatively regulates GO:0099536 GO:0051967
is_a GO:0050794 GO:0051967
regulates GO:0098916 GO:0051967
is_a GO:0023057 GO:0051967
is_a GO:0023051 GO:0051967
regulates GO:0023052 GO:0051967
regulates GO:0007154 GO:0051967
negatively regulates GO:0008150 GO:0051967
regulates GO:0035249 GO:0051967
negatively regulates GO:0007268 GO:0051967
is_a GO:0065007 GO:0051967
negatively regulates GO:0007267 GO:0051967
is_a GO:0099177 GO:0051967
negatively regulates GO:0009987 GO:0051967
regulates GO:0099537 GO:0051967
regulates GO:0099536 GO:0051967
is_a GO:0050789 GO:0051967
regulates GO:0050789 GO:0051967
is_a GO:0048523 GO:0051967
regulates GO:0008150 GO:0051967
is_a GO:0010648 GO:0051967
negatively regulates GO:0023052 GO:0051967
negatively regulates GO:0098916 GO:0051967

4 Synonyms

Name Type
down regulation of synaptic transmission, glutamatergic synonym
down-regulation of synaptic transmission, glutamatergic synonym
downregulation of synaptic transmission, glutamatergic synonym
inhibition of synaptic transmission, glutamatergic synonym