WormMine: Gene WBGene00227742

• WormBase Gene ID: WBGene00227742
• Gene Name: Bma-ced-11
• Sequence Name: Bm7481
• Organism: Brugia malayi
• Automated Description: Is affected by ivermectin based on RNA-seq studies. Is an ortholog of C. elegans ced-11. In C. elegans, ced-11 is involved in apoptotic process.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

4 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm7481a.1	Bm7481a.1		[unknown]
Transcript:Bm7481b.1	Bm7481b.1		[unknown]
Transcript:Bm7481c.1	Bm7481c.1		[unknown]
Transcript:Bm7481d.1	Bm7481d.1		[unknown]

Other

4 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm7481a	Bm7481a		[unknown]
CDS:Bm7481b	Bm7481b		[unknown]
CDS:Bm7481c	Bm7481c		[unknown]
CDS:Bm7481d	Bm7481d		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

• WormBaseAcedbConverter

0 Downstream Intergenic Region

7 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M120_vs_F120
	Transcripts that showed significantly lower expression in adult comparing to in microfilariae.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:Adult_vs_Micro_Downregulated
	Transcripts that showed significantly decreased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_F120_vs_F30
	Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M120_vs_M30
	Transcripts that showed significantly decreased expression in female B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_F120_vs_F42
	Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M120_vs_M42
	Transcripts that showed significantly decreased expression after 5 days of 300nM ivermectin exposure.	Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method).	WBPaper00049974:ivermectin_300nM_5-day_downregulated

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term