WormMine: Gene WBGene00227904

• WormBase Gene ID: WBGene00227904
• Gene Name: Bma-ufbp-1
• Sequence Name: Bm7643
• Organism: Brugia malayi
• Automated Description: Is affected by 20-hydroxyecdysone and ivermectin based on proteomic and RNA-seq studies. Is predicted to encode a protein with the following domains: DDRGK domain; DDRGK domain containing protein; Winged helix DNA-binding domain superfamily; and Winged helix-like DNA-binding domain superfamily. Is an ortholog of C. elegans ufbp-1.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

2 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm7643b.1	Bm7643b.1		[unknown]
Transcript:Bm7643a.1	Bm7643a.1		[unknown]

Other

2 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm7643b	Bm7643b		[unknown]
CDS:Bm7643a	Bm7643a		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

• WormBaseAcedbConverter

0 Downstream Intergenic Region

4 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M120_vs_M30
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_F120
	Proteins that showed significantly increased expression in parasites exposed to 20-hydroxyecdysone.	An empirical filter of proteins with more than two peptides identified, a P value <0.05 and a greater than two-fold change of differential expression, was applied to the data. The Bonferroni correction was applied to correct the P value for the proteins analyzed.	WBPaper00049261:20-hydroxyecdysone_upregulated_protein
	Transcripts that showed significantly increased expression after 48 hours of 100nM ivermectin exposure.	Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method).	WBPaper00049974:ivermectin_100nM_48h_upregulated

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term