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WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0060695 negative regulation of cholesterol transporter activity GO
Namespace  biological_process Obsolete  false
Description  Any process that decreases the rate, frequency, or extent of cholesterol transporter activity.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

29 Parents

Identifier Name Description
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0051234 establishment of localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0010876 lipid localization Any process in which a lipid is transported to, or maintained in, a specific location.
GO:0006869 lipid transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
GO:0033036 macromolecule localization Any process in which a macromolecule is transported to, or maintained in, a specific location.
GO:0032879 regulation of localization Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
GO:0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032368 regulation of lipid transport Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1905952 regulation of lipid localization Any process that modulates the frequency, rate or extent of lipid localization.
GO:0005319 lipid transporter activity Enables the directed movement of lipids into, out of or within a cell, or between cells.
GO:0044092 negative regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0120013 lipid transfer activity Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids.
GO:0032409 regulation of transporter activity Any process that modulates the activity of a transporter.
GO:0032410 negative regulation of transporter activity Any process that stops or reduces the activity of a transporter.
GO:1905953 negative regulation of lipid localization Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization.
GO:0032369 negative regulation of lipid transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0110114 negative regulation of lipid transporter activity Any process that decreases the frequency, rate, or extent of lipid transporter activity.
GO:0060695 negative regulation of cholesterol transporter activity Any process that decreases the rate, frequency, or extent of cholesterol transporter activity.
GO:0120020 cholesterol transfer activity Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
GO:0120015 sterol transfer activity Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.

40 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0110114 GO:0060695
negatively regulates GO:0120020 GO:0060695
is_a GO:0065007 GO:0060695
negatively regulates GO:0120020 GO:0060695
negatively regulates GO:0010876 GO:0060695
regulates GO:0051234 GO:0060695
regulates GO:0051179 GO:0060695
is_a GO:0051051 GO:0060695
is_a GO:0032879 GO:0060695
negatively regulates GO:0033036 GO:0060695
is_a GO:0032410 GO:0060695
is_a GO:0032409 GO:0060695
negatively regulates GO:0008150 GO:0060695
regulates GO:0006869 GO:0060695
negatively regulates GO:0006810 GO:0060695
is_a GO:0065009 GO:0060695
regulates GO:0003674 GO:0060695
is_a GO:0065007 GO:0060695
regulates GO:0005215 GO:0060695
regulates GO:0010876 GO:0060695
regulates GO:0033036 GO:0060695
negatively regulates GO:0120015 GO:0060695
is_a GO:0008150 GO:0060695
negatively regulates GO:0051179 GO:0060695
negatively regulates GO:0051234 GO:0060695
is_a GO:0044092 GO:0060695
negatively regulates GO:0120013 GO:0060695
regulates GO:0008150 GO:0060695
is_a GO:0032369 GO:0060695
is_a GO:0032368 GO:0060695

0 Synonyms