2 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00001569 | meg-3 | F52D2.4 | Caenorhabditis elegans |
| WBGene00016485 | meg-4 | C36C9.1 | Caenorhabditis elegans |
| WormBase ID | WBStrain00050724 | CGC Received | 2021-05-20 |
| Genotype | meg-3(ax4502[meg-3(F705A,Y708A,Y713A, N725A)::OLLAS]) meg-4(ax3052) X. | Laboratory | CGC |
| Made By | WBPerson27644 | Mutagen | CRISPR_Cas9 |
| Name | JH3861 | Outcrossed | x0 |
| Remark | 20% Maternal effect sterility on average, embryonic P granule defect, RNAi insensitivity. Engineered mutations in the endogenous meg-3 locus disrupt the binding and localization of PGL proteins to P granules in the early embryo while MEG-3 itself is still forms an asymmetric cytoplasmic gradient and granules. References: Smith, J. et al. Elife. 2016 Dec 3;5:e21337. doi: 10.7554/eLife.21337. PMID: 27914198 Schmidt H, bioRxiv 2020.10.15.340570 (2020) doi:10.1101/2020.10.15.340570. | Species | Caenorhabditis elegans |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00001569 | meg-3 | F52D2.4 | Caenorhabditis elegans |
| WBGene00016485 | meg-4 | C36C9.1 | Caenorhabditis elegans |
