1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00006763 | unc-26 | JC8.10 | Caenorhabditis elegans |
| WormBase ID | WBStrain00054666 | CGC Received | 2022-08-24 |
| Genotype | unc-26(pek288[R216Q]) IV. | Laboratory | CGC |
| Name | BJH728 | Outcrossed | x1 |
| Remark | unc-26(pek288) is a CRISPR-engineered R216Q substitution in unc-26/synaptojanin 1 associated with early-onset Parkinsonism (EOP) (Quadri et al., 2013; Krebs et al., 2013). This allele shows abnormal focal accumulation of ATG-9 in presynaptic nerve terminals, defects in activity-induced synaptic autophagy, and defects in sustained neurotransmission and locomotory behaviors in aging animals. Reference: Yang S, et al. Neuron. 2022 Mar 2;110(5):824-840.e10. PMID: 35065714 | Species | Caenorhabditis elegans |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00006763 | unc-26 | JC8.10 | Caenorhabditis elegans |
