3 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00004882 | smg-4 | F46B6.3 | Caenorhabditis elegans |
WBGene00006805 | unc-73 | F55C7.7 | Caenorhabditis elegans |
WBGene00013128 | dxbp-1 | Y52B11A.9 | Caenorhabditis elegans |
WormBase ID | WBStrain00055594 | CGC Received | 2023-08-23 |
Genotype | unc-73(az63) dxbp-1(az52) I; smg-4(az152) V. | Laboratory | CGC |
Made By | WBPerson713 | Mutagen | CRISPR_Cas9 |
Name | SZ355 | Outcrossed | x2 |
Remark | az52 is a CRISPR-engineered M107I missense allele of dxbp-1. az52 has no phenotype on its own, but suppresses unc-73(e936) and unc-73(az63) by promoting use of a cryptic splice site for an intron beginning with UU. smg-4(az152) provides an NMD deficient background allowing identification of out-of-frame mis-splicing in an RNA-seq experiment. Reference: Suzuki JMNGL, et al. PLoS Genet. 2022 Feb 10;18(2):e1010028. doi: 10.1371/journal.pgen.1010028. PMID: 35143478. | Species | Caenorhabditis elegans |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00004882 | smg-4 | F46B6.3 | Caenorhabditis elegans |
WBGene00006805 | unc-73 | F55C7.7 | Caenorhabditis elegans |
WBGene00013128 | dxbp-1 | Y52B11A.9 | Caenorhabditis elegans |