WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Strain :

WormBase ID  WBStrain00055594 CGC Received  2023-08-23
Genotype  unc-73(az63) dxbp-1(az52) I; smg-4(az152) V. Laboratory  CGC
Made By  WBPerson713 Mutagen  CRISPR_Cas9
Name  SZ355 Outcrossed  x2
Remark  az52 is a CRISPR-engineered M107I missense allele of dxbp-1. az52 has no phenotype on its own, but suppresses unc-73(e936) and unc-73(az63) by promoting use of a cryptic splice site for an intron beginning with UU. smg-4(az152) provides an NMD deficient background allowing identification of out-of-frame mis-splicing in an RNA-seq experiment. Reference: Suzuki JMNGL, et al. PLoS Genet. 2022 Feb 10;18(2):e1010028. doi: 10.1371/journal.pgen.1010028. PMID: 35143478. Species  Caenorhabditis elegans

3 Alleles

Public Name
az152
az63
az52

1 Data Sets

Name URL
WormBaseAcedbConverter  

3 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004882 smg-4 F46B6.3 Caenorhabditis elegans
WBGene00006805 unc-73 F55C7.7 Caenorhabditis elegans
WBGene00013128 dxbp-1 Y52B11A.9 Caenorhabditis elegans