2 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004187 | prp-8 | C50C3.6 | Caenorhabditis elegans |
| WBGene00006805 | unc-73 | F55C7.7 | Caenorhabditis elegans |
| WormBase ID | WBStrain00055587 | CGC Received | 2023-08-23 |
| Genotype | unc-73(e936) I; prp-8(az50) III. | Laboratory | CGC |
| Made By | WBPerson713 | Mutagen | CRISPR_Cas9 |
| Name | SZ197 | Outcrossed | x2 |
| Remark | prp-8(az50) is a T524S missense allele that affects cryptic splicing (5'ss choice) of unc-73(e936) to allow more UNC-73 protein to be produced. PRP-8 is the largest protein in the spliceosome (essential) with a role in all stages of splicing. Reference: Mayerle M, et al. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2193-2199. doi: 10.1073/pnas.1819020116. PMID: 30674666. | Species | Caenorhabditis elegans |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004187 | prp-8 | C50C3.6 | Caenorhabditis elegans |
| WBGene00006805 | unc-73 | F55C7.7 | Caenorhabditis elegans |
