WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0061684 chaperone-mediated autophagy GO

Namespace  biological_process Obsolete  false
Description  The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

23 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0051234 establishment of localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein.
GO:0055085 transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0009056 catabolic process A cellular process consisting of the biochemical pathways by which a living organism breaks down substances. This includes the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a protein. Includes protein modification.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0140104 molecular carrier activity Directly binding to a specific ion or molecule and delivering it either to an acceptor molecule or to a specific location.
GO:0061919 process utilizing autophagic mechanism A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway.
GO:0006914 autophagy The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation.
GO:0005515 protein binding Binding to a protein.
GO:0009057 macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0140597 protein carrier chaperone Binding to and carrying a protein between two different cellular components by moving along with the target protein.
GO:0005102 signaling receptor binding Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0030163 protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
GO:0051087 protein-folding chaperone binding Binding to a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
GO:0061684 chaperone-mediated autophagy The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.

35 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
has part GO:0005102 GO:0061684
has part GO:0140597 GO:0061684
has part GO:0051087 GO:0061684
is_a GO:0030163 GO:0061684
is_a GO:0006914 GO:0061684
has part GO:0009987 GO:0061684
is_a GO:0009987 GO:0061684
has part GO:0005488 GO:0061684
has part GO:0003674 GO:0061684
has part GO:0006810 GO:0061684
has part GO:0005515 GO:0061684
has part GO:0055085 GO:0061684
has part GO:0140104 GO:0061684
is_a GO:0061919 GO:0061684
is_a GO:0043170 GO:0061684
is_a GO:0019538 GO:0061684
has part GO:0008150 GO:0061684
is_a GO:0008150 GO:0061684
is_a GO:0008152 GO:0061684
is_a GO:0009056 GO:0061684
is_a GO:0009057 GO:0061684
is_a GO:0044238 GO:0061684
has part GO:0051234 GO:0061684
has part GO:0051179 GO:0061684
part of GO:0061684 GO:0061740
part of GO:0061684 GO:0061740
regulates GO:0061684 GO:1904714
regulates GO:0061684 GO:1904714
negatively regulates GO:0061684 GO:1904715
negatively regulates GO:0061684 GO:1904715

3 Synonyms

Name Type
CASA synonym
CMA synonym
chaperone-assisted selective autophagy synonym