WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0061857 endoplasmic reticulum stress-induced pre-emptive quality control GO

Namespace  biological_process Obsolete  false
Description  The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

28 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0033554 cellular response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0009056 catabolic process A cellular process consisting of the biochemical pathways by which a living organism breaks down substances. This includes the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a protein. Includes protein modification.
GO:0036211 protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GO:0043412 macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GO:0009057 macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0016567 protein ubiquitination The process in which one or more ubiquitin groups are added to a protein.
GO:0032446 protein modification by small protein conjugation A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.
GO:0043687 post-translational protein modification The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
GO:0070647 protein modification by small protein conjugation or removal A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.
GO:0006508 proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0051603 proteolysis involved in protein catabolic process The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
GO:0030163 protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
GO:0034976 response to endoplasmic reticulum stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
GO:0006511 ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
GO:0019941 modification-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.
GO:0043632 modification-dependent macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule.
GO:0010498 proteasomal protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
GO:0061857 endoplasmic reticulum stress-induced pre-emptive quality control The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome.

29 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
has part GO:0043161 GO:0061857
is_a GO:0034976 GO:0061857
has part GO:0010498 GO:0061857
has part GO:0008152 GO:0061857
has part GO:0030163 GO:0061857
is_a GO:0033554 GO:0061857
has part GO:0019941 GO:0061857
has part GO:0032446 GO:0061857
is_a GO:0009987 GO:0061857
has part GO:0008150 GO:0061857
has part GO:0006508 GO:0061857
is_a GO:0006950 GO:0061857
is_a GO:0051716 GO:0061857
has part GO:0043412 GO:0061857
has part GO:0043632 GO:0061857
is_a GO:0008150 GO:0061857
has part GO:0009056 GO:0061857
has part GO:0036211 GO:0061857
has part GO:0009057 GO:0061857
has part GO:0070647 GO:0061857
has part GO:0019538 GO:0061857
has part GO:0016567 GO:0061857
has part GO:0051603 GO:0061857
has part GO:0043170 GO:0061857
is_a GO:0050896 GO:0061857
has part GO:0043687 GO:0061857
has part GO:0009987 GO:0061857
has part GO:0006511 GO:0061857
has part GO:0044238 GO:0061857

2 Synonyms

Name Type
ER pQC synonym
ER stress-indiced pre-emptive quality control synonym