WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0070021 transforming growth factor beta ligand-receptor complex GO

Namespace  cellular_component Obsolete  false
Description  A protein complex that is formed by the association of a TGF-beta dimeric ligand with 2 molecules of each receptor molecule, TGF-beta type I receptor and TGF-beta type II receptor. The receptor molecules may form homo- or heterodimers but only once bound by the ligand.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

16 Parents

Identifier Name Description
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0110165 cellular anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
GO:1990234 transferase complex A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).
GO:0071944 cell periphery The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.
GO:0098796 membrane protein complex Any protein complex that is part of a membrane.
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
GO:0005886 plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0098797 plasma membrane protein complex Any protein complex that is part of the plasma membrane.
GO:1902554 serine/threonine protein kinase complex A protein complex which is capable of protein serine/threonine kinase activity.
GO:0061695 transferase complex, transferring phosphorus-containing groups A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:1902911 protein kinase complex A protein complex which is capable of protein kinase activity.
GO:0043235 receptor complex Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0098802 plasma membrane signaling receptor complex Any protein complex that is part of the plasma membrane and which functions as a signaling receptor.
GO:0070021 transforming growth factor beta ligand-receptor complex A protein complex that is formed by the association of a TGF-beta dimeric ligand with 2 molecules of each receptor molecule, TGF-beta type I receptor and TGF-beta type II receptor. The receptor molecules may form homo- or heterodimers but only once bound by the ligand.

16 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:1902554 GO:0070021
is_a GO:0098802 GO:0070021
is_a GO:0043235 GO:0070021
part of GO:0005575 GO:0070021
is_a GO:0098797 GO:0070021
part of GO:0110165 GO:0070021
part of GO:0005886 GO:0070021
is_a GO:0098796 GO:0070021
is_a GO:1902911 GO:0070021
is_a GO:0005575 GO:0070021
is_a GO:1990234 GO:0070021
is_a GO:0032991 GO:0070021
part of GO:0016020 GO:0070021
part of GO:0071944 GO:0070021
is_a GO:0061695 GO:0070021
is_a GO:1902494 GO:0070021

13 Synonyms

Name Type
TGF-beta 1:type II receptor:type I receptor complex synonym
TGF-beta receptor II-TGF-beta receptor I-TGF-beta1 complex synonym
TGF-beta ligand-receptor complex synonym
TGF-beta1-beta2 ligand-receptor complex synonym
TGF-beta1 ligand-receptor complex synonym
TGF-beta2 ligand-receptor complex synonym
TGF-beta1-type II receptor-type I receptor complex synonym
TGFbeta ligand-receptor complex synonym
TGFb ligand-receptor complex synonym
TGFbeta1-beta2 ligand-receptor complex synonym
TGFbeta1 ligand-receptor complex synonym
transforming growth factor beta1-type II receptor-type I receptor complex synonym
TGFbeta2 ligand-receptor complex synonym