GO:0022890
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inorganic cation transmembrane transporter activity
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Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage. |
GO:0022857
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transmembrane transporter activity
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Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
GO:0005215
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transporter activity
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Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells. |
GO:0003674
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molecular_function
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A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
GO:0008324
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monoatomic cation transmembrane transporter activity
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Enables the transfer of cation from one side of a membrane to the other. |
GO:0046873
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metal ion transmembrane transporter activity
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Enables the transfer of metal ions from one side of a membrane to the other. |
GO:0015075
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monoatomic ion transmembrane transporter activity
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Enables the transfer of an ion from one side of a membrane to the other. |
GO:0015318
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inorganic molecular entity transmembrane transporter activity
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Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon. |
GO:0005488
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binding
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The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
GO:0005515
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protein binding
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Binding to a protein. |
GO:0098772
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molecular function regulator activity
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A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition. |
GO:0015267
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channel activity
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Enables the energy-independent facilitated diffusion of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules. |
GO:0022803
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passive transmembrane transporter activity
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Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged. |
GO:0140678
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molecular function inhibitor activity
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A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target. |
GO:0099094
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ligand-gated monoatomic cation channel activity
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Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. |
GO:0015276
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ligand-gated monoatomic ion channel activity
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Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. |
GO:0005261
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monoatomic cation channel activity
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Enables the energy-independent facilitated diffusion of a monoatomic cation through a transmembrane aqueous pore or channel. |
GO:0005216
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monoatomic ion channel activity
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Enables the facilitated diffusion of a monoatomic ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size). |
GO:0022836
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gated channel activity
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Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus. |
GO:0022834
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ligand-gated channel activity
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Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. |
GO:0005244
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voltage-gated monoatomic ion channel activity
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Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
GO:0022832
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voltage-gated channel activity
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Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
GO:0005267
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potassium channel activity
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Enables the energy-independent facilitated diffusion of a potassium ion through a transmembrane aqueous pore or channel. |
GO:0015079
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potassium ion transmembrane transporter activity
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Enables the transfer of potassium ions (K+) from one side of a membrane to the other. |
GO:0005242
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inward rectifier potassium channel activity
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Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself. |
GO:0005249
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voltage-gated potassium channel activity
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Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
GO:0022843
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voltage-gated monoatomic cation channel activity
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Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
GO:0099106
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ion channel regulator activity
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Modulates the activity of a channel via direct interaction with it. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. |
GO:0016247
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channel regulator activity
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Binds to and modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. |
GO:0141108
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transporter regulator activity
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Binds to and modulates the activity of a transporter. |