WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0070551 endoribonuclease activity, cleaving siRNA-paired mRNA GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

3 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  enables

12 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0004519 endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
GO:0004518 nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids.
GO:0140640 catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify a nucleic acid.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0016788 hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond.
GO:0140098 catalytic activity, acting on RNA Catalytic activity that acts to modify RNA.
GO:0004521 RNA endonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
GO:0004540 RNA nuclease activity Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
GO:0070551 endoribonuclease activity, cleaving siRNA-paired mRNA Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.

11 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016891 GO:0070551
is_a GO:0003824 GO:0070551
is_a GO:0004518 GO:0070551
is_a GO:0004519 GO:0070551
is_a GO:0140098 GO:0070551
is_a GO:0004521 GO:0070551
is_a GO:0016788 GO:0070551
is_a GO:0004540 GO:0070551
is_a GO:0016787 GO:0070551
is_a GO:0140640 GO:0070551
is_a GO:0003674 GO:0070551

1 Synonyms

Name Type
argonaute endoribonuclease activity synonym