WormMine: Strain WBStrain00007654

• WormBase ID: WBStrain00007654
• CGC Received: 2012-04-16
• Genotype: sec-5(pk2357)/dpy-10(e128) II.
• Laboratory: CGC
• Made By: WBPerson1683
• Name: FZ282
• Remark: Heterozygotes segregate wild-type heterozygotes, Dpy, and sec-5 homozygotes (scrawny, small broods, abnormal gut appearance) sec-5 is homozygous maternal-effect lethal; M+Z- animals produce a few dead L1-L2 stage larvae with Vab defects. Based upon phenotype, pk2357 is a strong loss-of-function, but likely not a null allele; molecular lesion produces a premature stop at position 389. Reference: Frische EW, et al. EMBO J. 2007 Dec 12;26(24):5083-92. [NOTE: This strain was previously described as carrying pk2358, but pk2357 is the correct allele. Both pk2357 and pk2358 cause the same nonsense (amber) change.]
• Species: Caenorhabditis elegans

2 Alleles

Public Name
e128
pk2357

1 Data Sets

• WormBaseAcedbConverter

2 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001072	dpy-10	T14B4.7	Caenorhabditis elegans
WBGene00004752	sec-5	T23G7.4	Caenorhabditis elegans