2 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00001072 | dpy-10 | T14B4.7 | Caenorhabditis elegans |
WBGene00004752 | sec-5 | T23G7.4 | Caenorhabditis elegans |
WormBase ID | WBStrain00006437 | CGC Received | 2012-04-16 |
Genotype | sec-5(pk2357)/mIn1 [dpy-10(e128) mIs14] II. | Laboratory | CGC |
Made By | WBPerson516 | Name | DV2689 |
Remark | Heterozygotes segregate wild-type GFP+ heterozygotes, GFP+ Dpy, and sec-5 homozygotes (scrawny, small broods, abnormal gut appearance) sec-5 is homozygous maternal-effect lethal; M+Z- animals produce a few dead L1-L2 stage larvae with Vab defects. Pick GFP+ wild-type to maintain. Based upon phenotype, pk2357 is a strong loss-of-function, but likely not a null allele; molecular lesion produces a premature stop at position 389. Reference: Frische EW, et al. EMBO J. 2007 Dec 12;26(24):5083-92. [NOTE: This strain was previously described as carrying pk2358, but pk2357 is the correct allele. Both pk2357 and pk2358 cause the same nonsense (amber) change.] | Species | Caenorhabditis elegans |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00001072 | dpy-10 | T14B4.7 | Caenorhabditis elegans |
WBGene00004752 | sec-5 | T23G7.4 | Caenorhabditis elegans |