1 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00003085 | ccar-1 | Y37A1B.1 | Caenorhabditis elegans |
WormBase ID | WBStrain00008439 | CGC Received | 2018-06-11 |
Genotype | ccar-1(sda11) IV. | Laboratory | CGC |
Made By | WBPerson23891 | Mutagen | CRISPR_Cas9 |
Name | HMZ245 | Outcrossed | x4 |
Remark | Superficially wild-type except for a slightly shorter body length in adults. Crispr/Cas9 was used to create a 13 bp deletion in exon7 of ccar-1a; breakpoints: CTGATTCGGGAG/sda11/ATCGGAAGTTTC. sda11 is an isoform-specific deletion allele. It only affects the function of CCAR-1A and CCAR-1D, but not CCAR-1B and C. In addition, because CCAR-1D is not expressed in embryos,this allele can be used to specifically inactivate CCAR-1A (the full-length isoform that is the most similar to human CCAR1) during embryogenesis. Reference: Fu R, et al. J Cell Sci. 2018 May 10. | Species | Caenorhabditis elegans |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00003085 | ccar-1 | Y37A1B.1 | Caenorhabditis elegans |