WormMine: Gene WBGene00227872

• WormBase Gene ID: WBGene00227872
• Gene Name: Bma-pat-3
• Sequence Name: Bm7611
• Organism: Brugia malayi
• Automated Description: Is predicted to encode a protein with the following domains: Integrin beta subunit, VWA domain; Integrin domain superfamily; von Willebrand factor A-like domain superfamily; Integrin beta epidermal growth factor like domain 1; EGF-like domain; Integrin beta tail domain superfamily; Integrin plexin domain; Integrin beta N-terminal; Integrin beta subunit, tail; Integrin beta cytoplasmic domain; Integrin beta tail domain; Integrin beta subunit; Integrin beta subunit, cytoplasmic domain; Integrin beta, epidermal growth factor-like domain 1; Integrin beta chain VWA domain; and EGF-like domain, extracellular. Is an ortholog of C. elegans pat-3. In C. elegans, pat-3 is involved in several processes, including muscle cell cellular homeostasis; positive regulation of cellular component organization; and regulation of locomotion.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm7611.1	Bm7611.1		[unknown]

Other

1 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm7611	Bm7611		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

• WormBaseAcedbConverter

0 Downstream Intergenic Region

6 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_M30
	Transcripts that showed significantly lower expression in L3 larva comparing to in adult.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L3_vs_Adult_Downregulated
	Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_F120_vs_F30
	Transcripts that showed significantly lower expression in L4 larva comparing to in microfilariae.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L4_vs_Micro_Downregulated
	Transcripts that showed significantly lower expression in L4 larva comparing to in adult.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L4_vs_Adult_Downregulated
	Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP.	Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering.	WBPaper00045439:BM_Cluster_P5

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term