WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0090212 negative regulation of establishment of blood-brain barrier GO

Namespace  biological_process Obsolete  false
Description  Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

21 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0032502 developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
GO:0048856 anatomical structure development The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GO:0048468 cell development The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place.
GO:0048869 cellular developmental process A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
GO:0030154 cell differentiation The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
GO:0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GO:0060284 regulation of cell development Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
GO:0045596 negative regulation of cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
GO:0010721 negative regulation of cell development Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0051093 negative regulation of developmental process Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GO:0060856 establishment of blood-brain barrier Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
GO:0090210 regulation of establishment of blood-brain barrier Any process that modulates the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.
GO:0090212 negative regulation of establishment of blood-brain barrier Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.

31 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0065007 GO:0090212
negatively regulates GO:0060856 GO:0090212
is_a GO:0010721 GO:0090212
is_a GO:0090210 GO:0090212
negatively regulates GO:0060856 GO:0090212
is_a GO:0050794 GO:0090212
is_a GO:0050793 GO:0090212
regulates GO:0060856 GO:0090212
regulates GO:0009987 GO:0090212
negatively regulates GO:0048468 GO:0090212
regulates GO:0048856 GO:0090212
negatively regulates GO:0048869 GO:0090212
is_a GO:0065007 GO:0090212
regulates GO:0008150 GO:0090212
is_a GO:0008150 GO:0090212
is_a GO:0060284 GO:0090212
regulates GO:0030154 GO:0090212
is_a GO:0050789 GO:0090212
negatively regulates GO:0032502 GO:0090212
regulates GO:0048468 GO:0090212
is_a GO:0045596 GO:0090212
is_a GO:0048523 GO:0090212
is_a GO:0045595 GO:0090212
regulates GO:0048869 GO:0090212
is_a GO:0051093 GO:0090212
negatively regulates GO:0009987 GO:0090212
negatively regulates GO:0048856 GO:0090212
negatively regulates GO:0008150 GO:0090212
is_a GO:0048519 GO:0090212
negatively regulates GO:0030154 GO:0090212

1 Synonyms

Name Type
negative regulation of establishment of BBB synonym