WormBase Gene ID
|
RGD:2324431 | Gene Name | Prdm16 |
| Organism | Rattus norvegicus | Automated Description | Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; histone H3K9 methyltransferase activity; and transcription coactivator activity. Predicted to be involved in several processes, including negative regulation of granulocyte differentiation; positive regulation of cold-induced thermogenesis; and regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of brown fat cell differentiation; and regulation of DNA-templated transcription. Predicted to be located in aggresome; cytosol; and nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1LL. Orthologous to human PRDM16 (PR/SET domain 16); PARTICIPATES IN histone modification pathway; INTERACTS WITH (S)-nicotine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil. |
| Biotype | SO:0001217 | Genetic Position | :± |
