WormBase Gene ID
|
RGD:2313 | Gene Name | Cd74 |
| Organism | Rattus norvegicus | Automated Description | Predicted to enable several functions, including amyloid-beta binding activity; macrophage migration inhibitory factor binding activity; and signaling receptor binding activity. Predicted to contribute to cytokine binding activity. Involved in positive regulation of MAPK cascade. Predicted to be located in several cellular components, including external side of plasma membrane; lysosome; and multivesicular body. Predicted to be part of MHC class II protein complex; NOS2-CD74 complex; and macrophage migration inhibitory factor receptor complex. Predicted to be active in cell surface and cytoplasm. Orthologous to human CD74 (CD74 molecule); PARTICIPATES IN antigen processing and presentation pathway; tuberculosis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol. |
| Biotype | SO:0001217 | Genetic Position | :± |
