WormBase Gene ID
|
SGD:S000002186 | Gene Name | Mps1 |
| Organism | Saccharomyces cerevisiae | Automated Description | Dual-specificity kinase; required for SPB duplication and spindle checkpoint function in mitosis and meiosis; contributes to bi-orientation, promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; autophosphorylation required for function; substrates include SPB proteins (Spc42p, Spc110p, Spc98p), mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); detected in peroxisomes; similar to human Mps1p |
| Biotype | SO:0001217 | Genetic Position | :± |
