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WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0098686 hippocampal mossy fiber to CA3 synapse GO

Namespace  cellular_component Obsolete  false
Description  One of the giant synapses that form between the mossy fiber axons of dentate gyrus granule cells and the large complex spines of CA3 pyramidal cells. It consists of a giant bouton known as the mossy fiber expansion, synapsed to the complex, multiheaded spine (thorny excresence) of a CA3 pyramidal cell.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

18 Parents

Identifier Name Description
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0110165 cellular anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
GO:0120025 plasma membrane bounded cell projection A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
GO:0042995 cell projection A prolongation or process extending from a cell, e.g. a flagellum or axon.
GO:0098590 plasma membrane region A membrane that is a (regional) part of the plasma membrane.
GO:0098794 postsynapse The part of a synapse that is part of the post-synaptic cell.
GO:0045202 synapse The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
GO:0030054 cell junction A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.
GO:0043005 neuron projection A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
GO:0098793 presynapse The part of a synapse that is part of the presynaptic cell.
GO:0098984 neuron to neuron synapse A synapse in which pre and post-synaptic cells are neurons.
GO:0043197 dendritic spine A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
GO:0044309 neuron spine A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck.
GO:0043195 terminal bouton Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
GO:0097464 thorny excrescence Large complex spine protruding from a dendrite. Each excrescence is formed by a cluster of spine heads.
GO:1990026 hippocampal mossy fiber expansion Synaptic expansion of hippocampal mossy fiber axon that makes contact with the thorny excrescences of hippocampal CA3 pyramidal cell dendrites.
GO:0098686 hippocampal mossy fiber to CA3 synapse One of the giant synapses that form between the mossy fiber axons of dentate gyrus granule cells and the large complex spines of CA3 pyramidal cells. It consists of a giant bouton known as the mossy fiber expansion, synapsed to the complex, multiheaded spine (thorny excresence) of a CA3 pyramidal cell.

22 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
has part GO:1990026 GO:0098686
is_a GO:0098984 GO:0098686
has part GO:0097464 GO:0098686
has part GO:1990026 GO:0098686
is_a GO:0045202 GO:0098686
has part GO:0097464 GO:0098686
is_a GO:0045202 GO:0098686
has part GO:0043005 GO:0098686
has part GO:0043197 GO:0098686
has part GO:0016020 GO:0098686
has part GO:0120025 GO:0098686
has part GO:0043195 GO:0098686
is_a GO:0110165 GO:0098686
has part GO:0005575 GO:0098686
has part GO:0098590 GO:0098686
is_a GO:0005575 GO:0098686
is_a GO:0030054 GO:0098686
has part GO:0098794 GO:0098686
has part GO:0044309 GO:0098686
has part GO:0098793 GO:0098686
has part GO:0110165 GO:0098686
has part GO:0042995 GO:0098686

0 Synonyms