WormMine: Gene WBGene00233946

• WormBase Gene ID: WBGene00233946
• Gene Name: Bma-lin-53
• Sequence Name: Bm13685
• Organism: Brugia malayi
• Automated Description: Enriched in female and reproductive tract based on proteomic studies. Is predicted to encode a protein with the following domains: Histone-binding protein RBBP4 or subunit C of CAF1 complex; G-protein beta WD-40 repeat; WD40-repeat-containing domain superfamily; WD40/YVTN repeat-like-containing domain superfamily; WD domain, G-beta repeat; WD40 repeat; and Histone-binding protein RBBP4, N-terminal. Is an ortholog of C. elegans lin-53. In C. elegans, lin-53 is involved in several processes, including cell fate specification; embryonic digestive tract morphogenesis; and nematode male tail tip morphogenesis.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm13685.1	Bm13685.1		[unknown]

Other

1 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm13685	Bm13685		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

• WormBaseAcedbConverter

0 Downstream Intergenic Region

4 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Proteins that are enriched in productive tract of adult female Brugia malayi.	Protein quantitation was determined by normalized spectral abundance.Proteins with NSAF enrichment values of 2 or greater were were considered enriched within that fraction.	WBPaper00048706:productive-tract_enriched
	Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP.	Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering.	WBPaper00045439:BM_Cluster_P5
	Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP.	Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering.	WBPaper00045439:BM_Cluster_P16
	Proteins that were enriched in female animals.	Criteria used for protein identification included: two or more peptide matches, MASCOT score > 60, and P < 0.05.	WBPaper00041323:female-associated

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term