WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0102158 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain (2E)-enoyl-CoA. This reaction is the third (dehydration) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

4 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  enables
  enables

8 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016829 lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
GO:0016836 hydro-lyase activity Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
GO:0016835 carbon-oxygen lyase activity Catalysis of the breakage of a carbon-oxygen bond.
GO:0004300 enoyl-CoA hydratase activity Catalysis of the reaction: a 3-hydroxy-fatty acyl-CoA = a enoyl-CoA + H2O. This reaction usually occurs in the reverse direction, leading to the reduction of the double bound of enoyl-CoA in position 2 or 3. Specific reactions catalyzed include: a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O and a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O.
GO:0018812 3-hydroxyacyl-CoA dehydratase activity Catalysis of the reaction: a 3-hydroxy-fatty acyl-CoA = a (2E)-enoyl-CoA + H2O.
GO:0102158 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain (2E)-enoyl-CoA. This reaction is the third (dehydration) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0018812 GO:0102158
is_a GO:0004300 GO:0102158
is_a GO:0003674 GO:0102158
is_a GO:0016829 GO:0102158
is_a GO:0003824 GO:0102158
is_a GO:0016835 GO:0102158
is_a GO:0016836 GO:0102158

1 Synonyms

Name Type
very-long-chain 3-hydroxyacyl-CoA dehydratase activity synonym