WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0120330 rixosome complex GO

Namespace  cellular_component Obsolete  false
Description  A conserved RNA endonuclease complex required for spreading and epigenetic inheritance of heterochromatin. The rixosome contains six unique subunits: three structural subunits (Crb3, Rix1, and Ipi1) which form the core of the complex, and three catalytic subunits (the endonuclease Las1, the polynucleotide kinase Grc3, and the AAA-type ATPase Mdn1), which are involved in the processing of ribosomal RNA precursors. All subunits are essential for viability and are conserved from yeast to mammals, including humans.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

1 Ontology Annotations

Annotation Extension Qualifier
  part_of

7 Parents

Identifier Name Description
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0140535 intracellular protein-containing complex A protein-containing complex located intracellularly.
GO:1902555 endoribonuclease complex A protein complex which is capable of endoribonuclease activity.
GO:1905348 endonuclease complex A protein complex which is capable of endonuclease activity.
GO:0120330 rixosome complex A conserved RNA endonuclease complex required for spreading and epigenetic inheritance of heterochromatin. The rixosome contains six unique subunits: three structural subunits (Crb3, Rix1, and Ipi1) which form the core of the complex, and three catalytic subunits (the endonuclease Las1, the polynucleotide kinase Grc3, and the AAA-type ATPase Mdn1), which are involved in the processing of ribosomal RNA precursors. All subunits are essential for viability and are conserved from yeast to mammals, including humans.

6 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:1902555 GO:0120330
is_a GO:0005575 GO:0120330
is_a GO:0140535 GO:0120330
is_a GO:1902494 GO:0120330
is_a GO:1905348 GO:0120330
is_a GO:0032991 GO:0120330

1 Synonyms

Name Type
rix1 complex synonym