WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0140449 centromere-nuclear envelope anchor activity GO

Namespace  molecular_function Obsolete  false
Description  The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

21 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0051640 organelle localization Any process in which an organelle is transported to, and/or maintained in, a specific location.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0000278 mitotic cell cycle Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
GO:1903047 mitotic cell cycle process A process that is part of the mitotic cell cycle.
GO:0022402 cell cycle process The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.
GO:0007049 cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0031503 protein-containing complex localization A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.
GO:0005515 protein binding Binding to a protein.
GO:0030674 protein-macromolecule adaptor activity An adaptor activity that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.
GO:0060090 molecular adaptor activity The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
GO:0050000 chromosome localization Any process in which a chromosome is transported to, or maintained in, a specific location.
GO:0043495 protein-membrane adaptor activity The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle.
GO:0097240 chromosome attachment to the nuclear envelope The process in which chromatin is anchored to the nuclear envelope.
GO:0072765 centromere localization A cellular localization process in which a centromere/kinetochore is transported to, or maintained in, a specific location.
GO:0072766 centromere clustering at the mitotic interphase nuclear envelope The process in which chromatin, or kinetochores are anchored to the nuclear envelope. This process involves the microtubule cytoskeleton, and nuclear tethering factors and is responsible for the Rabl-like configuration of chromosomes in the interphase nuclei.
GO:0098653 centromere clustering The process by which centromeres/kinetochores become localized to clusters.
GO:0140449 centromere-nuclear envelope anchor activity The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location.

21 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0043495 GO:0140449
part of GO:0072766 GO:0140449
part of GO:0097240 GO:0140449
part of GO:0007049 GO:0140449
part of GO:0000278 GO:0140449
part of GO:0031503 GO:0140449
part of GO:0009987 GO:0140449
is_a GO:0060090 GO:0140449
has part GO:0005488 GO:0140449
part of GO:1903047 GO:0140449
has part GO:0003674 GO:0140449
is_a GO:0030674 GO:0140449
part of GO:0008150 GO:0140449
has part GO:0005515 GO:0140449
part of GO:0022402 GO:0140449
part of GO:0072765 GO:0140449
part of GO:0098653 GO:0140449
part of GO:0051179 GO:0140449
is_a GO:0003674 GO:0140449
part of GO:0051640 GO:0140449
part of GO:0050000 GO:0140449

7 Synonyms

Name Type
centromere-inner nuclear envelope anchor activity synonym
centromere nuclear envelope tether activity synonym
chromosome, centromeric region-nuclear envelope anchor activity synonym
centromere-inner nuclear envelope tether activity synonym
nuclear envelope-centromere tether activity synonym
nuclear envelope-centromere anchor activity synonym
centromere nuclear envelope anchor activity synonym