WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0140545 ATP-dependent protein disaggregase activity GO

Namespace  molecular_function Obsolete  false
Description  An ATP-dependent molecular chaperone activity that mediates the solubilization of ordered protein aggregates.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

13 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.
GO:0017111 ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.
GO:0016887 ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0140657 ATP-dependent activity A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0005515 protein binding Binding to a protein.
GO:0140776 protein-containing complex destabilizing activity A molecular function that involves direct binding to one of the subunits of a protein-containing complex and promoting the dissociation of one or many subunits. This often happens by changing the conformation of the protein being bound, which decreases its affinity for the rest of the complex.
GO:0140545 ATP-dependent protein disaggregase activity An ATP-dependent molecular chaperone activity that mediates the solubilization of ordered protein aggregates.

13 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
has part GO:0005515 GO:0140545
is_a GO:0140657 GO:0140545
is_a GO:0140776 GO:0140545
is_a GO:0003674 GO:0140545
has part GO:0003824 GO:0140545
has part GO:0016817 GO:0140545
has part GO:0016818 GO:0140545
has part GO:0017111 GO:0140545
has part GO:0016462 GO:0140545
has part GO:0005488 GO:0140545
has part GO:0003674 GO:0140545
has part GO:0016787 GO:0140545
has part GO:0016887 GO:0140545

2 Synonyms

Name Type
protein unfoldase activity synonym
protein disaggregase activity synonym