WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0140616 iodotyrosine deiodinase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalyzes the reaction: 2 iodide + L-tyrosine + 2 NADP+ = 3,5-diiodo-L-tyrosine + H+ + 2 NADPH. Note that this activity has only been demonstrated in the direction of 3-deiodination. 3-bromo-L-tyrosine and 3-chloro-L-tyrosine can also be used as substrates.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

1 Ontology Annotations

Annotation Extension Qualifier
  enables

5 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0046992 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y.
GO:0140616 iodotyrosine deiodinase activity Catalyzes the reaction: 2 iodide + L-tyrosine + 2 NADP+ = 3,5-diiodo-L-tyrosine + H+ + 2 NADPH. Note that this activity has only been demonstrated in the direction of 3-deiodination. 3-bromo-L-tyrosine and 3-chloro-L-tyrosine can also be used as substrates.

4 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0046992 GO:0140616
is_a GO:0016491 GO:0140616
is_a GO:0003824 GO:0140616
is_a GO:0003674 GO:0140616

4 Synonyms

Name Type
tyrosine iodinase activity synonym
iodide peroxidase-tyrosine iodinase activity synonym
monoiodotyrosine deiodinase activity synonym
iodotyrosine deiodase activity synonym