WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0140631 aldehyde dehydrogenase (NAD+) inhibitor activity GO

Namespace  molecular_function Obsolete  false
Description  Binds to and stops, prevents or reduces the activity of aldehyde dehydrogenase (NAD+).

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

14 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0005515 protein binding Binding to a protein.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0030234 enzyme regulator activity Binds to and modulates the activity of an enzyme.
GO:0004857 enzyme inhibitor activity Binds to and stops, prevents or reduces the activity of an enzyme.
GO:0140678 molecular function inhibitor activity A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.
GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.
GO:0004029 aldehyde dehydrogenase (NAD+) activity Catalysis of the reaction: an aldehyde + H2O + NAD+ = a carboxylate + 2 H+ + NADH.
GO:0140631 aldehyde dehydrogenase (NAD+) inhibitor activity Binds to and stops, prevents or reduces the activity of aldehyde dehydrogenase (NAD+).

17 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
negatively regulates GO:0004029 GO:0140631
is_a GO:0004857 GO:0140631
negatively regulates GO:0016620 GO:0140631
regulates GO:0003674 GO:0140631
has part GO:0005488 GO:0140631
has part GO:0003674 GO:0140631
negatively regulates GO:0004030 GO:0140631
has part GO:0005515 GO:0140631
is_a GO:0140678 GO:0140631
negatively regulates GO:0016903 GO:0140631
regulates GO:0003824 GO:0140631
is_a GO:0098772 GO:0140631
is_a GO:0003674 GO:0140631
negatively regulates GO:0003674 GO:0140631
is_a GO:0030234 GO:0140631
negatively regulates GO:0003824 GO:0140631
negatively regulates GO:0016491 GO:0140631

0 Synonyms