WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0140869 miRNA inhibitor activity via base-pairing GO

Namespace  molecular_function Obsolete  false
Description  Stops, prevents or reduces the activity of miRNA-mediated gene silencing activity by base-pairing with a target miRNA. An example of this activity is mediated by long non-coding RNAs (lncRNAs).

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

10 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0003723 RNA binding Binding to an RNA molecule or a portion thereof.
GO:0003676 nucleic acid binding Binding to a nucleic acid.
GO:0005515 protein binding Binding to a protein.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0140678 molecular function inhibitor activity A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0061980 regulatory RNA binding Binding to a small regulatory RNA, a short RNA (usually 50-200 nt long) that is either independently transcribed or processed from a longer RNA by an RNAse enzyme.
GO:0035198 miRNA binding Binding to a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.
GO:0140869 miRNA inhibitor activity via base-pairing Stops, prevents or reduces the activity of miRNA-mediated gene silencing activity by base-pairing with a target miRNA. An example of this activity is mediated by long non-coding RNAs (lncRNAs).

11 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0140678 GO:0140869
is_a GO:0035198 GO:0140869
has part GO:0005488 GO:0140869
has part GO:0003674 GO:0140869
has part GO:0005515 GO:0140869
is_a GO:0003723 GO:0140869
is_a GO:0061980 GO:0140869
is_a GO:0098772 GO:0140869
is_a GO:0003676 GO:0140869
is_a GO:0003674 GO:0140869
is_a GO:0005488 GO:0140869

6 Synonyms

Name Type
miRNA base-pairing repressor activity synonym
base-pairing target-directed miRNA suppressor activity synonym
miRNA inhibitor activity synonym
miRNA binding involved in posttranscriptional gene silencing synonym
miRNA sponge synonym
base-pairing target-directed microRNA suppressor activity synonym