WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0141016 G/T mismatch-specific thymine-DNA glycosylase activity GO

Namespace  molecular_function Obsolete  false
Description  Hydrolyzes mismatched double-stranded DNA and polynucleotides, releasing free thymine and leaving an apyrimidinic (AP) site.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

11 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0140640 catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify a nucleic acid.
GO:0140097 catalytic activity, acting on DNA Catalytic activity that acts to modify DNA.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0016798 hydrolase activity, acting on glycosyl bonds Catalysis of the hydrolysis of any glycosyl bond.
GO:0019104 DNA N-glycosylase activity Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
GO:0000700 mismatch base pair DNA N-glycosylase activity Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds Catalysis of the hydrolysis of any N-glycosyl bond.
GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site.
GO:0141016 G/T mismatch-specific thymine-DNA glycosylase activity Hydrolyzes mismatched double-stranded DNA and polynucleotides, releasing free thymine and leaving an apyrimidinic (AP) site.

10 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0008263 GO:0141016
is_a GO:0016798 GO:0141016
is_a GO:0016787 GO:0141016
is_a GO:0016799 GO:0141016
is_a GO:0003674 GO:0141016
is_a GO:0140097 GO:0141016
is_a GO:0019104 GO:0141016
is_a GO:0140640 GO:0141016
is_a GO:0003824 GO:0141016
is_a GO:0000700 GO:0141016

0 Synonyms