WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0180019 Knl1/Spc105 complex GO

Namespace  cellular_component Obsolete  false
Description  A kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans and yeast respectively, it consists of KNL1/Spc105p and ZWINT/Kre28p.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

17 Parents

Identifier Name Description
GO:0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0005622 intracellular anatomical structure A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.
GO:0110165 cellular anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0043228 membraneless organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0043232 intracellular membraneless organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0005694 chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0099080 supramolecular complex A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber.
GO:0000940 outer kinetochore The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
GO:0000776 kinetochore A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
GO:0000775 chromosome, centromeric region The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
GO:0000779 condensed chromosome, centromeric region The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
GO:0098687 chromosomal region Any subdivision of a chromosome along its length.
GO:0000793 condensed chromosome A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
GO:0180019 Knl1/Spc105 complex A kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans and yeast respectively, it consists of KNL1/Spc105p and ZWINT/Kre28p.

18 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0032991 GO:0180019
part of GO:0000940 GO:0180019
part of GO:0099080 GO:0180019
part of GO:0043229 GO:0180019
is_a GO:0005575 GO:0180019
part of GO:0005694 GO:0180019
part of GO:0043232 GO:0180019
part of GO:0110165 GO:0180019
part of GO:0005622 GO:0180019
part of GO:0043228 GO:0180019
part of GO:0000793 GO:0180019
part of GO:0005575 GO:0180019
part of GO:0043226 GO:0180019
part of GO:0000775 GO:0180019
part of GO:0000776 GO:0180019
part of GO:0000779 GO:0180019
part of GO:0098687 GO:0180019
part of GO:0032991 GO:0180019

0 Synonyms