WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:1900260 negative regulation of RNA-dependent RNA polymerase activity GO

Namespace  biological_process Obsolete  false
Description  Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

19 Parents

Identifier Name Description
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0140640 catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify a nucleic acid.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0140098 catalytic activity, acting on RNA Catalytic activity that acts to modify RNA.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0051338 regulation of transferase activity Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0016772 transferase activity, transferring phosphorus-containing groups Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0016779 nucleotidyltransferase activity Catalysis of the transfer of a nucleotidyl group from one compound (donor) to another (acceptor).
GO:0034062 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end.
GO:0097747 RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template.
GO:0003968 RNA-directed RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.
GO:0044092 negative regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0043086 negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme.
GO:0051348 negative regulation of transferase activity Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
GO:1900260 negative regulation of RNA-dependent RNA polymerase activity Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.

23 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0065007 GO:1900260
negatively regulates GO:0003968 GO:1900260
is_a GO:0051348 GO:1900260
negatively regulates GO:0003968 GO:1900260
negatively regulates GO:0140640 GO:1900260
is_a GO:0050790 GO:1900260
negatively regulates GO:0003674 GO:1900260
negatively regulates GO:0140098 GO:1900260
regulates GO:0003674 GO:1900260
negatively regulates GO:0016779 GO:1900260
is_a GO:0008150 GO:1900260
is_a GO:0044092 GO:1900260
is_a GO:0051338 GO:1900260
is_a GO:0043086 GO:1900260
regulates GO:0016740 GO:1900260
negatively regulates GO:0016740 GO:1900260
negatively regulates GO:0097747 GO:1900260
negatively regulates GO:0016772 GO:1900260
is_a GO:0065007 GO:1900260
regulates GO:0003824 GO:1900260
is_a GO:0065009 GO:1900260
negatively regulates GO:0034062 GO:1900260
negatively regulates GO:0003824 GO:1900260

91 Synonyms

Name Type
down-regulation of RNA-dependent ribonucleate nucleotidyltransferase activity synonym
down-regulation of RNA synthetase activity synonym
down-regulation of RNA-dependent RNA replicase activity synonym
down-regulation of RNA-dependent RNA polymerase activity synonym
down-regulation of transcriptase synonym
down-regulation of RNA-directed RNA polymerase activity synonym
downregulation of PB1 proteins synonym
downregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed) synonym
downregulation of phage f2 replicase synonym
downregulation of PB2 proteins synonym
downregulation of RDRP synonym
downregulation of polymerase L synonym
downregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity synonym
downregulation of ribonucleic acid replicase activity synonym
downregulation of ribonucleic replicase activity synonym
downregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity synonym
downregulation of RNA nucleotidyltransferase (RNA-directed) activity synonym
downregulation of ribonucleic synthetase activity synonym
downregulation of RNA synthetase activity synonym
downregulation of RNA replicase activity synonym
downregulation of RNA-dependent RNA polymerase activity synonym
downregulation of RNA-dependent ribonucleate nucleotidyltransferase activity synonym
downregulation of RNA-directed RNA polymerase activity synonym
downregulation of RNA-dependent RNA replicase activity synonym
inhibition of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed) synonym
downregulation of transcriptase synonym
inhibition of PB2 proteins synonym
inhibition of PB1 proteins synonym
inhibition of polymerase L synonym
inhibition of phage f2 replicase synonym