WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:1901925 negative regulation of protein import into nucleus during spindle assembly checkpoint GO

Namespace  biological_process Obsolete  false
Description  Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p).

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

15 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0009607 response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
GO:0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
GO:0071495 cellular response to endogenous stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
GO:0071216 cellular response to biotic stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
GO:0072396 response to cell cycle checkpoint signaling A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling.
GO:0072414 response to mitotic cell cycle checkpoint signaling A process that occurs in response to signals generated as a result of mitotic cell cycle checkpoint signaling.
GO:0072417 response to spindle checkpoint signaling A process that occurs in response to signals generated as a result of spindle checkpoint signaling.
GO:0072485 response to spindle assembly checkpoint signaling A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling.
GO:0072476 response to mitotic spindle checkpoint signaling A process that occurs in response to signals generated as a result of mitotic cell cycle spindle checkpoint signaling.
GO:0072479 response to mitotic cell cycle spindle assembly checkpoint signaling A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling.
GO:1901925 negative regulation of protein import into nucleus during spindle assembly checkpoint Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p).

14 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0072479 GO:1901925
is_a GO:0071216 GO:1901925
is_a GO:0072417 GO:1901925
is_a GO:0072414 GO:1901925
is_a GO:0072485 GO:1901925
is_a GO:0071495 GO:1901925
is_a GO:0072396 GO:1901925
is_a GO:0072476 GO:1901925
is_a GO:0009719 GO:1901925
is_a GO:0009607 GO:1901925
is_a GO:0009987 GO:1901925
is_a GO:0050896 GO:1901925
is_a GO:0008150 GO:1901925
is_a GO:0051716 GO:1901925

3 Synonyms

Name Type
Kap121p transport inhibitory pathway synonym
negative regulation of protein import into nucleus during mitotic cell cycle spindle assembly checkpoint synonym
KTIP synonym